NEURO

Incidental imaging findings are abnormalities of potential clinical significance discovered unintentionally that are not related to the symptoms that prompted the test [1]. Their identification frequently leads to adverse psychological and social consequences [2,3]. Knowledge of the concept of incidental findings prior to imaging may enhance patient autonomy and reduce anxiety in the event that an incidental finding is subsequently identified [4]. However, the risk of incidental findings is frequently not discussed in clinical practice. from Journal of the Neurological Sciences https://ift.tt/2HhHjYw

Cannabis use is on the rise both as medical treatment and recreational use. There is evidence that cannabis can cause hallucinations and psychosis especially with heavy and prolonged use. Parkinson's disease (PD) carries an increased risk for development of hallucinations and psychosis. It is possible that cannabis may exacerbate this risk and result in earlier and greater amounts of hallucinations and psychosis in this vulnerable population. A literature review was performed to determine the answer to that question. from Journal of the Neurological Sciences https://ift.tt/2IVfDJk

Herpes simplex viruses (HSV) are neurotropic and known to cause central nervous system (CNS) infections. We aimed to describe the clinical and imaging features of cerebrovascular complications in patients with HSV CNS infections. from Journal of the Neurological Sciences https://ift.tt/34ktH7x

Research productivity is a key criterion for applicant selection reported by residency program directors. Research volume reported on neurosurgery residency applications has risen steadily over the past decade. from Journal of the Neurological Sciences https://ift.tt/3kpE8Mw

NMOSD is an inflammatory disorder of the central nervous system that primarily affects the optic nerves and spinal cord. Rituximab (RTX) is a monoclonal antibody directed against CD20, an epitope expressed on pre-B and mature B cells. It has of wide use in several antibody-mediated autoimmune diseases. from Journal of the Neurological Sciences https://ift.tt/2Tek9o3

To the editor, from Journal of the Neurological Sciences https://ift.tt/3oeUSsg

It is generally agreed that optimal head positioning is an important consideration in acute stroke management regime. However, there is limited literature investigating the effect of head positioning changes on cerebrovascular physiology in acute ischemic stroke (AIS). We aim to assess cerebral autoregulation (CA) and associated hemodynamic responses during gradual head positioning (GHP) changes, between AIS and controls. from Journal of the Neurological Sciences https://ift.tt/35hgxHu

We thank Sun et al. for their interest in our article on mechanical thrombectomy in patients with left ventricular assist device (LVAD) [1]. We absolutely concur with their views that further studies are necessary to confirm our findings and there is a need for elucidating the best treatment strategy in this high-risk population. from Journal of the Neurological Sciences https://ift.tt/34cbYPj

To examine 1) the major drivers of index hospitalization and 3-year post-acute follow-up care, 2) cost for rehabilitation and homecare, and 3) indirect cost from lost productivity after acute ischemic stroke (AIS) and intracerebral hemorrhage (ICH). from Journal of the Neurological Sciences https://ift.tt/3lYXTL8

Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex is a disappearing neurodegenerative disorder of apparent environmental origin formerly hyperendemic among Chamorros of Guam-USA, Japanese residents of the Kii Peninsula, Honshu Island, Japan and Auyu-Jakai linguistic groups of Papua-Indonesia. The most plausible etiology is exposure to genotoxins in seed of neurotoxic cycad plants formerly used for food and/or medicine. Primary suspicion falls on methylazoxymethanol (MAM), the aglycone of cycasin and on the non-protein amino acid β-N-methylamino-L-alanine, both of which are metabolized to formaldehyde. from Journal of the Neurological Sciences https://ift.tt/31cetiN

The supplementary motor area (SMA) is involved in several aspects of motor control and its can be associated to a contralateral motor deficit and speech disorders. After the resection of low-grade gliomas, this syndrome is diffusely reported but it is rarely investigated in high-grade gliomas. SMA deficits may resolve completely or with minor sequelae within weeks. Whether this condition of transient deficit affects survival, was not previously investigated, and is not currently understood. from Journal of the Neurological Sciences https://ift.tt/2FyDcX2

Cardiac emboli secondary to atrial fibrillation (AF) commonly cause large vessel occlusions (LVO) that require endovascular thrombectomy (EVT) to restore cerebral circulation. Whether the outcome of patients with AF diagnosed after the index stroke (newAF) differs from that of AF-patients in which AF was known before stroke (kAF) remains unknown. from Journal of the Neurological Sciences https://ift.tt/3nPqogc

To investigate multiple sclerosis (MS) optical coherence tomography (OCT) cross-sectional correlations with central nervous system (CNS) magnetic resonance imaging (MRI). from Journal of the Neurological Sciences https://ift.tt/2GKK843

Myocardial infarction (MI) is a known cause of cerebral infarction. We assessed whether the size and location of MI is associated with the risk of cerebral infarction. from Journal of the Neurological Sciences https://ift.tt/33TdfuM

The current COVID-19 pandemic has resulted in a cumulative total of over 34.8 million cases. Over 1 million deaths have now been reported globally, with the majority being reported in the region of the Americas (55%), followed by Europe (23%). Approximately 50% of cases worldwide are in the 25–64 age group (WHO situation report; accessed October 52,020) though the majority of deaths have occurred in older persons. from Journal of the Neurological Sciences https://ift.tt/37cSNaj

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the loss of upper and lower motor neurons that results in progressive paralysis and muscular atrophy. There are many molecules and genes involved in neuromuscular degeneration in ALS; among these, matrix metalloproteinases (MMPs). MMPs play an important role in the pathology of ALS, and MMP-1, 2, 3, and 9 might serve as disease progression markers. Tissue inhibitors of metalloproteinases (TIMPS) might also function as progression markers in ALS because they participate in regulating the proteolytic activity of MMPs. from Journal of the Neurological Sciences https://ift.tt/34MeevH

We aimed to describe the use and findings of cranial computerized tomography (CT-head), spine and brain magnetic resonance imaging (MRI-spine/MRI-brain) in Lyme neuroborreliose (LNB). from Journal of the Neurological Sciences https://ift.tt/3iSluuZ

Parkinson's disease (PD) is characterized by a range of classic motor symptoms and heterogeneous nonmotor symptoms that affect patients' quality of life (QoL). Studies have individually reported the effect of either motor or nonmotor symptoms on patients' QoL; however, a thorough assessment of the symptoms that have the greatest influence on QoL is limited. This JAQPAD study examined the effect of both motor and nonmotor symptoms and patient demographics on QoL in a large population of patients with PD in Japan. from Journal of the Neurological Sciences https://ift.tt/30OPbXO

To investigate underlying cerebral small vessel disease (CSVD) in patients with mixed cerebral hemorrhages patterns and phenotype them according to the contribution of the two most common sporadic CSVD subtypes: cerebral amyloid angiopathy (CAA) vs. hypertensive arteriopathy (HA). from Journal of the Neurological Sciences https://ift.tt/3jLAzji

Cerebral Micro-infarcts; the Hidden Missing Link to Vascular Cognitive Decline. from Journal of the Neurological Sciences https://ift.tt/3nw9oLZ