Congratulations Jackson N. Cagle, Wissam Deeb , Robert S. Eisinger , Rene Molina , Enrico Opri , Marshall T. Holland, Kelly D. Foote , Michael S. Okun , and Aysegul Gunduz on the publication of “Lead Repositioning Guided by Both Physiology and Atlas Based Targeting in Tourette Deep Brain Stimulation,” in Tremor and Other Hyperkinetic Movements. Abstract Background: The centromedian (CM) region of the thalamus is a common target for deep brain stimulation (DBS) treatment for Tourette Syndrome (TS). However, there are currently no standard microelectrode recording or macrostimulation methods to differentiate CM thalamus from other nearby structures and nuclei. Case Report: Here we present a case of failed conventional stereotactic targeting in TS DBS. Postoperative local field potential recordings (LFPs) showed features including beta power desynchronization during voluntary movement and thalamo-cortical phase amplitude coupling at rest. These findings suggested that the DBS lead