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Microglia Tweak Retinogeniculate Pathways during Visual Circuit Refinement

Cheadle et al. reveal that microglia expressing TWEAK facilitate synapse elimination through a novel, non-phagocytic mechanism in the retinogeniculate pathway during visual circuit development. This mechanism is experience-dependent and occurs through the local binding of TWEAK to postsynaptic Fn14.

from journals https://ift.tt/35liHHx
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