Cancer frequency among the patients with myotonic dystrophy in the South Korean population using the national health insurance database

Myotonic dystrophies (DMs) are autosomal dominant, multisystemic disorders characterized by myotonia and progressive muscle weakness [1]. DM type 1 (DM1) results from a trinucleotide repeat expansion (CTG) in the myotonic dystrophy protein kinase (DMPK) gene [2,3], and DM type 2 (DM2) is caused by an expansion of CCTG repeats in the CCHC-type zinc finger, nucleic acid binding protein (CNBP) gene [4]. DM1 is the most common adult muscular dystrophy with a prevalence ranging between 0.5 and 18.1 per 100,000 [5].

from Journal of the Neurological Sciences https://ift.tt/34LMNDs