Huntington's disease: A new evidence of neurovascular dysfunction

Huntington's disease (HD) is an autosomal-dominant neurodegenerative disorder characterized by motor, cognitive and psychiatric abnormalities. The onset of the disease is usually in the third-fourth decade of life, however 5–10% of subjects become symptomatic before 20 years (“juvenile Huntington's disease”). The disease is caused by an abnormal CAG repeat expansion in exon 1 of the “huntingtin” gene localized on the short arm of chromosome 4. This mutation leads to expression of the mutant huntingtin (mHtt) protein which forms toxic intracellular aggregates that are ubiquitously found in the central nervous system and peripheral tissues [1].

from Journal of the Neurological Sciences https://ift.tt/3fznLKw

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Menopause Symptoms Reduced by Cold Water Swimming

Cold water swimming significantly eases menopausal symptoms. Surveying 1114 women, with 785 experiencing menopause, researchers found improvements in anxiety, mood swings, low mood, and hot flushes among participants. from Neuroscience News https://ift.tt/9AqHsEa

UPI: Kids with psych disorders most likely to take dangerous viral challenges

The “choking game” — and other clearly ill-advised and dangerous internet challenges — leave many parents wondering what drives teens to take the bait and participate. Now, a new study suggests that an underlying psychological disorder may be one reason why some kids jump at online dares such as the “Bird Box” challenge, where people walk around blindfolded, and the Tide Pod challenge, daring people to eat laundry detergent. (January 28, 2019) Read the full article here from Brain Health Daily http://bit.ly/2DIWHbD

Mapping the Human Brain Over a Lifetime

Researchers aim to map and track cellular changes in the human brain over a lifetime. from Neuroscience News https://ift.tt/jF6YeSX

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