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Use of Multimodal Imaging and Clinical Biomarkers in Carriers of C9orf72 Repeat Expansion

This case-control study examines the use of fluorine 18–labeled fluorodeoxyglucose positron emission tomographic imaging to detect glucose metabolic changes in individuals who are presymptomatic carriers of a mutation in the C9orf72 gene that leads to amyotrophic lateral sclerosis and frontotemporal dementia.

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