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APOE4 triggers early breakdowns in the blood-brain barrier

This shows a brainAPOE4, a gene implicated as a risk factor for Alzheimer's disease, triggers leaks in the blood-brain barrier. The damage to capillaries APOE4 causes correlates with increased levels of cyclophilin, a protein that causes the inflammation that is a signature of early Alzheimer's.

from Neuroscience News https://ift.tt/3eX1Tt7
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