Teaching NeuroImages: Autoimmune glial fibrillary acidic protein meningoencephalomyelitis

A 73-year-old woman with myelodysplastic syndrome presented with 2 months of decline in cognition and mobility, accompanied by headache and weight loss. Examination revealed a somnolent woman with symmetric cogwheel rigidity, bradykinesia, arm myoclonus, and hyperreflexia. Brain MRI showed leptomeningeal, linear/stippled parenchymal, and ependymal enhancement (figure 1). Spine MRI demonstrated nonenhancing cervicothoracic cord signal change and circumferential enhancement of conus medullaris with central canal enhancement (figure 2). CSF was inflammatory with glial fibrillary acidic protein (GFAP)–immunoglobulin G (IgG). The patient responded promptly to IV methylprednisolone. GFAP-IgG identifies a severe but highly corticosteroid-responsive autoimmune meningoencephalomyelitis with distinctive MRI findings.^1,2

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Menopause Symptoms Reduced by Cold Water Swimming

Cold water swimming significantly eases menopausal symptoms. Surveying 1114 women, with 785 experiencing menopause, researchers found improvements in anxiety, mood swings, low mood, and hot flushes among participants. from Neuroscience News https://ift.tt/9AqHsEa

Balancing Act: The Mixed Blessings of Solitude on Mental Health

A new study examines the nuanced impact of solitude on mental health among adults aged 35 and older in the UK and US. Tracking 178 participants over 21 days, the research found no definitive optimal balance between solitude and social interaction. from Neuroscience News https://ift.tt/oD5jKd8

Handwriting Boosts Brain Connectivity and Learning

Handwriting, compared to typing, results in more complex brain connectivity patterns, enhancing learning and memory. This study used EEG data from 36 students to compare brain activity while writing by hand and typing. from Neuroscience News https://ift.tt/0bklQBj

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