Cerebral amyloid angiopathy-related transient focal neurological episodes (CAA-TFNEs): A well-defined clinical-radiological syndrome

Cerebral amyloid angiopathy (CAA), is a common degenerative small vessel disease of the ageing brain resulting from progressive amyloid deposition, predominantly in small arteries and arterioles of the cortex and leptomeninges [1]. CAA is more relevant than ever, since it can now be readily diagnosed during life using validated neuroimaging criteria (aka the Boston criteria) [2,3], particularly with the widespread use of blood-sensitive T2* MRI sequences. Consequently, the dominant theme of CAA-related clinical research and practice in the last decade or so has been the growing appreciation of the diverse manifestations of the disease [4,5].

from Journal of the Neurological Sciences https://ift.tt/2BMP9ms