Thermoregulation via Temperature-Dependent PGD2 Production in Mouse Preoptic Area

Single-cell RNA-seq combined with whole-cell patch-clamp recording identifies PGD2 synthase enriched in temperature-sensitive neurons in the medial preoptic area of mouse, which detects brain temperature increase and mediates body temperature decrease via PGD2 receptor DP1 expressed in ventral medial preoptic area.

from journals http://bit.ly/2wlWEhw