Skip to main content

The Evolution of Phase-Separated TDP-43 in Stress

In this issue of Neuron, Gasset-Rosa et al. (2019) and Mann et al. (2019) demonstrate that cytoplasmic inclusions containing aggregated phosphorylated TDP-43 can evolve through three pathways: direct aggregation or phase-separated intermediates involving ejection from stress granules or seeding with exogenous fibrils. Interestingly, seeding with exogenous fibrils also induces cytoplasmic aggregates of nuclear pore proteins.

from journals http://bit.ly/2v7vZEt
Labels:

Comments

Post a Comment

Popular posts from this blog

Menopause Symptoms Reduced by Cold Water Swimming

Cold water swimming significantly eases menopausal symptoms. Surveying 1114 women, with 785 experiencing menopause, researchers found improvements in anxiety, mood swings, low mood, and hot flushes among participants. from Neuroscience News https://ift.tt/9AqHsEa
Post a Comment
Read more

Handwriting Boosts Brain Connectivity and Learning

Handwriting, compared to typing, results in more complex brain connectivity patterns, enhancing learning and memory. This study used EEG data from 36 students to compare brain activity while writing by hand and typing. from Neuroscience News https://ift.tt/0bklQBj
Post a Comment
Read more

More Education, Longer Life: Global Study Reveals Link

A new study reveals that higher education levels significantly reduce the risk of death, regardless of age, sex, location, or background. Researchers found that each additional year of education decreases death risk by two percent, with 18 years of education lowering it by 34 percent. from Neuroscience News https://ift.tt/oeK38Fk
Post a Comment
Read more