Disruption of RNA binding proteins with widespread perturbations of the transcriptome is at the heart of several neurological diseases. Nussbacher et al. review the diverse mechanisms by which this occurs (reduced expression, increased aggregation, and sequestration by repeat-containing RNAs and proteins), and emerging therapeutic approaches to ameliorate these pathologies.
from journals http://bit.ly/2vawspm
from journals http://bit.ly/2vawspm
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