Author response: Deep brain stimulation improves restless legs syndrome in patients with Parkinson disease

I thank Marques et al. for the interest in our study,¹ the clarification, and the thoughtful comments. Their study reported that patients with Parkinson disease (PD) with postoperative emergence of restless legs syndrome (RLS) had higher preoperative and postoperative dopamine agonist (DA) doses, and had a lower percentage of DA reduction after deep brain stimulation (DBS),² not "more significant reduction" as misinterpreted from our article.¹ This underscores the controversy surrounding this issue since there are reports of RLS emergence after DBS in patients with PD with greater reduction of dopaminergic therapy,³ less reductions,² and no correlation with degree of medication reduction.¹ We thank Marques et al. for bringing attention to the complexity of this topic, and the call for further research in this area that might shed light on the effects of DBS on RLS symptoms and the mechanisms of RLS in general.

from Neurology recent issues http://bit.ly/2GQVaSh

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Menopause Symptoms Reduced by Cold Water Swimming

Cold water swimming significantly eases menopausal symptoms. Surveying 1114 women, with 785 experiencing menopause, researchers found improvements in anxiety, mood swings, low mood, and hot flushes among participants. from Neuroscience News https://ift.tt/9AqHsEa

UPI: Kids with psych disorders most likely to take dangerous viral challenges

The “choking game” — and other clearly ill-advised and dangerous internet challenges — leave many parents wondering what drives teens to take the bait and participate. Now, a new study suggests that an underlying psychological disorder may be one reason why some kids jump at online dares such as the “Bird Box” challenge, where people walk around blindfolded, and the Tide Pod challenge, daring people to eat laundry detergent. (January 28, 2019) Read the full article here from Brain Health Daily http://bit.ly/2DIWHbD

The emerging influential role of microglia in neurology

In her most catchily titled book, The Angel and the Assassin , Donna Jackson Nakazawa highlighed nerve cells which have hitherto been very little acknowledged – microglia . Long ignored as bit players in the big league of the nervous system, Nakazawa colourfully illustrated what many neuroscientists are beginning to realise: the small size of microglia belies their huge influence ; m icroglia are, after all, the defence force of the nervous system, protecting the brain from microbial invaders . In keeping with their small size, their role is to surreptitiously present the antigens of invading bugs to T cells , the toffs who actually carry out the final hatchet job . It is therefore not surprising that any dysfunction of microglia will come with significant clinical consequences . By GerryShaw – Own work , CC BY-SA 3.0 , Link The most important clinical fallout of dysfunctional microglia appears to be the emergence of dementia. It is indeed spec...

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