Motor unit potential changes in myofibrillar myopathy

Both conventional and quantitative electromyography (Q-EMG) studies have been conducted in relatively large samples in common myopathies such as muscle dystrophies, inflammatory myopathies and mitochondrial myopathies [1,2]. These studies report a rather modest diagnostic sensitivity, with lowest sensitivity values found in mitochondrial myopathies [3]. In contrast, motor unit action potential (MUP) analysis appears very sensitive in sporadic inclusion body myositis, where a decreased mean duration is observed in 94% of the patients [4].

from Journal of the Neurological Sciences https://ift.tt/2Hwfxpt