Skip to main content

RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43

Mann et al. describe an optogenetic technique to generate neurotoxic TDP-43 assemblies found in ALS/FTD patient neurons. They show that aberrant phase transitions of TDP-43 are driven by its RNA binding status and develop an approach to prevent this neurotoxic process.

from journals https://ift.tt/2EAO7ME

Comments

Popular posts from this blog

Reading Minds to Understand Human Tool Use

Combining brain imaging data with machine learning, researchers make new discoveries about how the brain controls the hand. The findings could lead to the development of more advanced neuroprosthetics. from Neuroscience News https://ift.tt/3tv7BbC

Rethinking the Link Between Cannabinoids and Learning

Disrupted cannabinoid signaling impairs learning by altering behavioral states. from Neuroscience News https://ift.tt/2Hrmr0g