Conclusions Our study provides additional information about DGM involvement in patients with MS, showing the presence of alterations of different MR imaging metrics as a possible reflection of neurodegenerative and neuroinflammatory processes in these structures. Furthermore, our results demonstrate the presence of a different behavior of DGM atrophy in MS phenotypes, with subcortical GM volume loss mainly determined by global WM lesion burden in patients with RRMS, while local microstructural damage, along with susceptibility changes, account for the development of the significant DGM atrophy occurring in patients with PMS.
Combining brain imaging data with machine learning, researchers make new discoveries about how the brain controls the hand. The findings could lead to the development of more advanced neuroprosthetics. from Neuroscience News https://ift.tt/3tv7BbC
According to study group
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Our study provides additional information about DGM involvement in patients with MS, showing the presence of alterations of different MR imaging metrics as a possible reflection of neurodegenerative and neuroinflammatory processes in these structures. Furthermore, our results demonstrate the presence of a different behavior of DGM atrophy in MS phenotypes, with subcortical GM volume loss mainly determined by global WM lesion burden in patients with RRMS, while local microstructural damage, along with susceptibility changes, account for the development of the significant DGM atrophy occurring in patients with PMS.