Author: Edited by Mario Incayawar and Sioui Maldonado Bouchard ISBN: 9780190248253 Binding: Hardcover Publication Date: 09 September 2020 Price: $125.00 from journals https://ift.tt/35iTY72
This study determines whether selective serotonin reuptake inhibitor use among survivors of primary intracerebral hemorrhage was associated with intracerebral hemorrhage recurrence and decreased severity of depressive symptoms. from journals https://ift.tt/3juXe2R
This randomized clinical trial evaluates the efficacy and safety of fingolimod, 0.5 mg, and fingolimod, 0.25 mg, compared with glatiramer acetate, 20 mg, and examines whether these fingolimod doses show superior efficacy to glatiramer acetate for the treatment of adult patients with relapsing-remitting multiple sclerosis. from journals https://ift.tt/2QlnSie
This cohort study examines the reporting of dementia on death certificates in the US and the mortality burden associated with dementia. from journals https://ift.tt/2Ysay04
This Viewpoint highlights the complex role of racism in stroke, and suggests a framework for understanding its effects. from journals https://ift.tt/326O85e
This randomized clinical trial examines which medication (pregabalin, duloxetine, nortriptyline, or mexiletine) is most effective for reducing neuropathic pain and best tolerated in patients with cryptogenic sensory polyneuropathy. from journals https://ift.tt/2CxCrMe
Social group dynamics are highly complex. In this issue of Neuron, Anpilov et al. use a novel wireless optogenetics device to demonstrate that the repeated stimulation of oxytocin neurons modulates pro-social and agonistic behaviors in a time- and context-dependent manner. from journals https://ift.tt/3gctsxU
How synapses assemble remains unknown. In this issue of Neuron, Held et al. (2020) demonstrate that Cav2-type voltage-gated calcium channels do not mediate presynaptic assembly. Moreover, the channel-associated protein α2δ localizes independently, suggesting additional functions for this auxiliary protein. from journals https://ift.tt/2Ehhlm0
In this issue, Brignani, Raj, et al. show that Netrin-1 from distinct sources controls neuronal migrations into the substantia nigra. Remarkably, one source of Netrin −1 is forebrain axons traversing the midbrain, and this is required for proper GABAergic neuronal migration into the substantia nigra pars reticulata. from journals https://ift.tt/3hc7rQV
Many brain areas represent aspects of learned behavior. How do representations differ between regions? In this issue of Neuron, Kyriazi et al. (2020) show how the amygdala and prefrontal cortex use distinct strategies to code features of a complex task. from journals https://ift.tt/2FELpIU
This case report describes a man who applied topical metronidazole to his decubitus ulcers and experienced an uncommon neurological complication. from journals https://ift.tt/31FitaW
This case-control study examines the prevalence of salvageable tissues 16 hours or more from the time the patient was last known well after ischemic stroke due to emergent large vessel occlusion and investigates the effectiveness of endovascular treatment in delayed large vessel occlusion. from journals https://ift.tt/2PHTqhQ
In this issue of Neuron, Vandael et al. (2020) reveal that post-tetanic potentiation at dentate gyrus mossy fiber synapses is induced by natural activity patterns. This plasticity is mediated by an increase in readily releasable vesicle pool size and is extended in the absence of activity, forming a “pool engram.” from journals https://ift.tt/39YfL3Y
Memory formation is a dynamic process and sleep is part of it. Consolidation of memories relies on finely orchestrated brain activities occurring during the post-learning sleep period. In this issue of Neuron, Kumar and colleagues provide evidence that the activity of adult-born hippocampal neurons during REM sleep is critical for the consolidation of episodic memory. from journals https://ift.tt/3a4ZgmT
A circuit understanding of how perception links to response requires integrating neural connectivity, activity, and behavior. In this issue of Neuron, Tasaka et al. (2020) target neurons activated by ultrasonic pup vocalizations and discover a functional synaptic network embedded through acoustically selective TeA neurons that help link the calls to a discriminative maternal behavioral response. from journals https://ift.tt/2EObNPX
Characterizing the brain’s ability to adapt to changing environments has been at the forefront of neuroscience for decades. In this issue of Neuron, Newbold et al. (2020) build on this neuroplasticity work using precision neuroimaging and arm casting to unmask previously unknown pulses of spontaneous activity. from journals https://ift.tt/30sYAEA
Although 62 years have elapsed since the first report of hereditary deafness in a mouse strain, the molecular mechanism of hair cell mechanotransduction remains elusive. Three recent studies present crucial insights into the molecular crux of hair cell mechanotransduction machinery. from journals https://ift.tt/3gy8wlT
The Viewpoint discusses the controversy about whether families should have the right to delay apnea testing to determine death by neurologic critera. from journals https://ift.tt/33sobjb