NEURO

Stroke outcomes could be a quality indicator across the continuum of care and inform stroke management policymaking. However, this topic has rarely to date been studied directly. from Journal of the Neurological Sciences http://bit.ly/2v0dPEo

Differential diagnosis between Parkinson's disease (PD) and atypical parkinsonism, such as multiple system atrophy (MSA), can be difficult, especially in the early stages of the disease. Deep learning using neural networks (NNs) makes possible the prediction of the diagnosis using various types of biomarkers, unlike conventional linear statistics. We aimed to differentiate the Parkinson's variant of MSA (MSA-P) from PD both in the early stages by clinical utilization of NN analyses before the hot cross-bun and putaminal rim imaging features of MSA appeared. from Journal of the Neurological Sciences http://bit.ly/2OZoFUo

Flat panel imaging for emergent large vessel occlusion can be acquired prior to mechanical thrombectomy (MT). In this study, we examined patients undergoing MT with computed tomography angiography (CTA) to determine agreement on the site of occlusion and CTA collateral score (CS). from Journal of the Neurological Sciences http://bit.ly/2uVxoxX

This study aimed to explore clinical correlates of repetitive speech disorders in patients with Parkinson's disease (PD). from Journal of the Neurological Sciences http://bit.ly/2P4NXQZ

Wearable technology used in Parkinson's disease (PD) research has become an increasing focus of interest in this field. Our group assessed the feasibility, clinical correlation, reliability, and acceptance of smartwatches in order to quantify arm resting tremors in PD patients. An Android application on a smartwatch was used to obtain raw data from the smartwatch's gyroscopes. Twenty-two PD patients were consecutively recruited and followed for 1 year. Arm rest tremors were video filmed and scored by two independent raters using the motor subscale of the Unified Parkinson's Disease Rating Scale (UPDRS-III). from Journal of the Neurological Sciences http://bit.ly/2I9EQy4

Swayne A, Lane M, Brown H, et al. 084 Treating yourself: a glucocorticoid secreting tumour suppressing myasthenia gravis. J Neurol Neurosurg Psychiatry 2018;89:A34. doi: 10.1136/jnnp-2018-ANZAN.83 In this meeting abstract, the author Cullen O'Gorman who is affiliated with the Department of Neurology, Princess Alexandra Hospital, Brisbane, QLD, Australia should have appeared third in the author list. from Journal of Neurology, Neurosurgery & Psychiatry recent issues http://bit.ly/2UrGX6E

Kaneko K, Sato DK, Nakashima I, et al . CSF cytokine profile in MOG-IgG+ neurological disease is similar to AQP4-IgG+ NMOSD but distinct from MS: a cross-sectional study and potential therapeutic implications. J Neurol Neurosurg Psychiatry 2018;89:927–36. doi: 10.1136/jnnp-2018-317969 In table 2 of this paper there were errors in the title headings. The terms AQP4-IgG should not be appearing in columns 4 and 6. In the final heading, the v should also be removed. from Journal of Neurology, Neurosurgery & Psychiatry recent issues http://bit.ly/2FZLinR

The frontotemporal dementia (FTD) spectrum is a heterogeneous group of neurodegenerative syndromes with overlapping clinical, molecular and pathological features, all of which challenge the design of clinical trials in these conditions. To date, no pharmacological interventions have been proven effective in significantly modifying the course of these disorders. This study critically reviews the construct and methodology of previously published randomised controlled trials (RCTs) in FTD spectrum disorders in order to identify limitations and potential reasons for negative results. Moreover, recommendations based on the identified gaps are elaborated in order to guide future clinical trial design. A systematic literature review was carried out and presented in conformity with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. A total of 23 RCTs in cohorts with diagnoses of behavioural and language variants of FTD, corticobasal syndrome and progressive supran